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Science Sparks @ ACTREC
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 20 April 2026 |
Vol. No. 15 ; Issue No.731 |
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Publications
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1. Thapa B, Fatima E, Gupta A, Shukla E, Verma D, Singh A, Parashar S, Sarita, Bawankule D, Khan F, Chanda D, Kode J, Negi A (2026). Benzofluorene derivative exhibits antiproliferative effect against leukemia by tubulin polymerisation inhibition. Sustainable Chemistry One World.
2. Suthahar T, Veerabhadrappa J, Munshi R, Anbu Raj E, Gota V, Ivaturi V, Mallayasamy S (2026). Factors influencing pharmacokinetics of 5-fluorouracil in cancer patients: a systematic review of population pharmacokinetic models. European Journal of Clinical Pharmacology. 82(5):126.
3. Mehrotra M, Shenoy P, Sakpal A, Chakraborty S, Ray P (2026). p53-R248W evades doxorubicin mediated cell death through collective alteration in TOP2A and CYP1A1 genes in cancer cells. Biochemical and Biophysical Research Communications.
4. Zilli T, Zaorsky N, Maitre P, Desai N, Seibert T, Sun Y, Dess T, Tree A, Koontz B (2026). Metastasis-directed Therapy in Oligometastatic Castration-resistant Prostate Cancer: From Chasing the Last Metastasis to Changing the Game?International Journal of Radiation Oncology,Biology,Physics. 125 (1): 11-14.
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Interesting Reads
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Colombo N, Zsiros E, Parma G, Rulli E, Sebastianelli A, Bidzinski M, Gallardo C, Matanes E, Hasegawa K, Kose F, Magallanes-Maciel M, Herbertson RA, Ananda S, Kroep JR, de Melo AC, Debruyne PR, Kim JW, Sehouli J, Pierre ME, Hietanen S, Zamagni C, Lu X, Monk BJ, Coleman RL, Peng X, Yamada K, Bogusz AM, De La Motte Rouge T, Wu X; ENGOT-ov65/KEYNOTE-B96 investigators. Pembrolizumab plus weekly paclitaxel in platinum-resistant recurrent ovarian cancer (ENGOT-ov65/KEYNOTE-B96): a multicentre, randomised, double-blind, phase 3 study. Lancet. 407(10538):1525-1537.
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Video of the Week
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| Precision Medicine for Cancer: The End of the Beginning |
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Do You Know?
In 2015, FDA approved talimogene laherparepvec (T-VEC) for the treatment of some patients with metastatic melanoma that cannot be surgically removed.
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Cancer News
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Global trial shows novel treatment for triple-negative breast cancer nearly doubles survival.
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MedicalXpress, 16/04/2026
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In total, 644 TNBC patients were enrolled in TROPION-Breast02 across multiple sites across the globe, including the United States, Canada, Europe, China, Korea, Japan and Singapore. Patients were randomly assigned to two treatment arms:...
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Scientists supercharge immune cells to destroy cancer more effectively
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Sciencedaily, 16/04/2026
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Researchers have found a way to make cancer-killing immune cells more powerful and precise. By adding specific signaling components, they boosted the cells' readiness to attack tumors. Surprisingly, briefly suppressing the cells with a drug before use made them even more effective later....
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New biomarker predicts prognosis and treatment response in colorectal cancer
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News-Medical.Net, 14/04/2026
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First, the potential of CTHRC1(+) CAFs as predictive markers of treatment response was studied across 17 cohorts comprising samples from nearly 3,000 patients. Next, tumor cell RNA was analysed at the single-cell level to identify the most promising cell populations. Finally, the proteins they expressed were...
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2026 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
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